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Last Modified: 4/7/2025 Location: FL, PR, USVI Business: Part A, Part B

PC-ACE Upgrade/Installation Instructions

To provide the most up-to-date information within PC-ACE, the software program is updated quarterly.
The most current software is PC-ACE version 6.6 released on April 7, 2025.

Section 1: Preparing to Install or Upgrade

For new installations, verify your system meets the minimum hardware and software requirements found in the Getting Started with PC-ACE document.
For upgrades only, perform a system backup from your current version of PC-ACE. For instructions on completing a system backup, please refer to the PC-ACE User Guide. The backup is only recommended for data restore needs in the unexpected case of an upgrade error. The backup data is not needed with a routine upgrade as it is programmed to automatically retain all data. Close the PC-ACE software program after the backup is complete. The software cannot be open for the upgrade.

Section 2: Downloading PC-ACE

Internet Download:
Read the important notes below before starting the download process:
The below steps may differ slightly based on your internet browser. Microsoft Edge is the recommended browser.
An installation password is required for the PC-ACE software. This password was provided in your EDI PC-ACE approval letter. If you receive an error message, or cannot locate the password, please contact Medicare EDI using the contact information at the bottom of this document.
You may need to temporarily disable any firewall and virus scanning software (for example: Norton, Symantec, Microsoft, McAfee).
Upgrade – follow these instructions if you currently have the First Coast version of PC-ACE installed on your computer.
1. Access the PC-ACE software page.
2. Click on the “PC-ACE current version (version number) update download for existing users” link.
3. Open and run the .zip file.
CMS requires you to use the most current version of the software program and to eliminate the use of prior versions within 90 days of a new version’s release.
Full Version (New Installation) – follow these instructions if you are installing PC-ACE for the first time or if you do not currently have the First Coast version of the software.
1. Access the PC-ACE software page.
2. Click on the “PC-ACE current version (version number) full download for new users” link.
3. Open and run the .zip file.
CD-ROM Download:
Insert the PC-ACE CD-ROM into your CD-ROM drive. Navigate to the drive that your CD-Writer is installed on. Select the setup.exe for the full download, or the pcaceup.exe for the upgrade. Select “Run”.

Section 3: For Network Users

Network Installations
PC-ACE must be installed to a drive that is accessible to all workstation on the network that require PC-ACE.
1. Using the Windows Explorer, locate the “CLIENT32.EXE” fine in the “WINPCACE” directory within the network drive. Execute this program directly from the network drive (do not copy this file to your local drive.)
Troubleshooting item: Confirm each workstation has access to the network drive containing the “WINPCACE” directory (via a mapped drive letter.)
Follow the on-screen wizard steps to complete the installation. You will be prompted to select a local destination drive. The PC-ACE program and client support files will be installed to the “WINPCACE” directory on the selected local drive. In addition, a PC-ACE shortcut icon will be created and placed on the Windows desktop.
Repeat steps 1 and 2 (from Section 3) for each workstation that required PC-ACE access.
Please contact your network administrator for support when installing PC-ACE on a network.
Network Upgrades
When downloading a PC-ACE upgrade to a network, it will recognize that an update has been made to the server drive and you will be prompted to begin the client upgrade the next time PC-ACE is run from the client PC. Follow the on-screen wizard to complete the client upgrades.
Sign up for the Electronic Data Interchange eNews for all future upgrade notifications and important information about the software.
In you have questions or require assistance, please contact us at:
Florida and U.S. Virgin Islands: (888) 670-0940
Puerto Rico: (888) 875-9779
First Coast Service Options (First Coast) strives to ensure that the information available on our provider website is accurate, detailed, and current. Therefore, this is a dynamic site and its content changes daily. It is best to access the site to ensure you have the most current information rather than printing articles or forms that may become obsolete without notice.