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UB-04 billing information

December 23, 2025
The Official UB-04 Data Specifications Manual 2025, copyrighted by the American Hospital Association, is the only official source of UB-04 billing information adopted by the National Uniform Billing Committee (NUBC).

Modifier 66 fact sheet

March 30, 2026
Surgeons append modifier 66 to claims indicating they were on a team of surgeons performing a specific procedure on the same patient during the same operative session. Billing modifier 66 requires documentation to support the claim.

Acute kidney injury

February 16, 2026
Read this article, which provides billing guidance for acute kidney injury.

Modifier 25 flowchart

March 27, 2026
Use this decision flowchart to assist in correctly applying the 25 modifier.

Modifier 57 flowchart

March 27, 2026
Use this decision flowchart to assist in correctly applying the 57 modifier.

Ending AX modifier requirements for acute kidney injury (AKI) and end stage renal disease (ESRD)

February 27, 2026
Effective July 1, 2026, new billing instructions apply related to no longer submitting the AX modifier and hemodiafiltration and AKI claims.
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